PTFC-2 Fraction Collector

Semi Automated Tablet Dissolution

The PTFC-2 Fraction Collector can be attached to any PTA Dissolution Bath. Using either a Peristaltic-, Syringe- or a valve-less Piston Pump the dissolution media is directly sampled into covered glass vials inside the sampling dish of the PTFC-2.
Depending on the system configuration sampling information such as interval timing and total number of sampling sequences is either programed at the keyboard of the connected dissolution bath or directly at the PTFC-2 panel (DFC 70).
Individual Pinch Valves separately connected to each vessel are used to switch the liquid flow. Previous to a sampling sequence the media is circulated within a closed loop betwen the dissolution vessels and the PTFC-2. As soon as the concentration of the media is equilibrated the pinch valves open for samling. At the end of a sampling sequence all tubes are automatically emptied. Adding an extra set of valves and a pump with more channels the PTFC-2 can also re-fill the sampled media.

A typical semi automated Dissolution Testing System including a PTFC-2 consist of:

PTWS 100 Dissolution Bath, In-Situ Sampling Probes, PTFE tubing, 8-channel Peristaltic Pump, PTFC-2 Fraction Collector. Automated media refilling is possible using a 16-channel pump and the re-filling valve block inside the PTFC-2