DFC 610 including PTWS 610 Bath

Semi Automated Dissolution Testing

Whenever automated sampling from a Dissolution Bath is required the PTFC-2 fraction collector together with a pump offers an ideal choice. The control of the Fraction Collector with respect to sampling times, dosage volumes, media refilling and pump drive is done via the keyboard and Display or the Method Filing System of the PTWS 610 dissolution bath. Enter sampling times, program EPE auto sampling time or call  the required Testing Method and connect the system components together for a semi automated operation.
The PTWS 610 is equipped with a manual Tablet Drop Magazine, the Auto Sampling Probe EPE, which lowers the sampling tubes into the vessels while sampling and rises them at the end of a cycle out of the media. The EPE can be equipped with an ITM Individual Media Temperature Probe System, recording the media temperature while sampling. Correctly positioned sampling tubes only immersed while sampling, equal sampling times and standardized solvent transport offer a high standard of reproducability and reliability for dissolution tests.
Also the economical aspect will show that automated sampling offers advantages as the operator does only need to fill the flasks and introduce the samples, thereafter the system operates automatically. Using a PTFC-2 fraction collector means that the way of analysis is open for spectrometer or LC. The filled vials within the vial dish are manually moved to the analiser and either manually injected or transferred to an autoinjection system.

A typical semi automated DFC 610 dissolution test system is composed of the following instruments:
PTWS 610 Dissolution Bath, manual Tablet Drop Magazine, EPE Auto Sampling System, ITM Temperature Monitoring System, PTFE tubing installation, 8-channel Peristaltic-, Piston-, or Syringe Pump, and a PT-FC2 Fraction Collector. Refilling can be automated, too using a 16 channel pump and a refilling valve block inside the PTFC-2.